The climacteric state is a physiological phase of transition in the life of every woman: it is the period characterised by a set of symptoms and hormonal changes that precede and follow the menopause. Essentially, the climacteric state or climacteric syndrome marks the transition from fertile to non-reproductive age.

Understanding its manifestations is essential to manage this life phase in the best way, especially in an age such as the one we are living in, where attention to the health and well-being of people at different stages of life is becoming increasingly a priority.

For pharmaceutical companies, understanding and responding to the specific needs of these age groups means not only contributing significantly to people’s quality of life, but also seizing new market opportunities. So let’s see what climacteric ishow long it lasts and why it is important to have a targeted range of supplements on offer to respond effectively to these needs.

What is climacteric?

The difference between climacteric and menopause lies in the fact that the term “menopause” specifically refers to the last menstrual cycle. However, when we talk about climacteric, we are referring to the changes that occur both before and after this event, in the so-called perimenopause, which marks a progressive change in the female hormone balance.

During the climacteric period, the body undergoes significant changes as a result of the alteration of hormone levels, in particular oestrogens, due to the progressive decline of ovarian activity. This period is divided into three phases:

  •  pre-menopause, which begins when the menstrual cycle first becomes irregular and symptoms appear;
  •  menopause, i.e. the last menstruation, 6/12 months after their absence (amenorrhoea);
  •  post-menopause, i.e. the phase after the last spontaneous menstruation.

What are climacteric symptoms?

The symptoms of climacteric syndrome vary significantly from woman to woman, especially in terms of intensity and frequency. However, there are recurrent symptoms. Among the most common are hot flushes,  menstruation-related changes, insomnia, but also vaginal drynessweight gain and mood disorders.

But why does climacteric have these effects on the female body? As we age, the ovaries (the female gonads) begin to react less effectively to gonadotropins released by the pituitary gland (GnRH), to the follicle stimulating hormone (FSH) and to the luteinizing hormone (LH). This change involves a reduction in the duration of the follicular phase, leading to shorter and irregular menstrual cyclesless frequent ovulations and also a reduction in the production of progesterone and oestrogens.

Climacteric: at what age it occurs and how long it lasts

The end of ovarian cyclic activity and female fertility generally occur between the ages of 45 and 55. When this happens before the age of 40, it is considered premature menopause, but if it happens after the age of 55, it is late menopause.

The age of onset of climacteric, however, varies significantly according to genetic factors, lifestyle and general health conditions. Its duration is equally variable, including a few years before and after menopause.

How can climacteric be managed?

The management of climacteric symptoms may include both pharmacological and non-pharmacological approaches.

Pharmacological therapies include:

  • hormone replacement therapy (HRT), with the administration of oestrogens alone or oestrogens combined with progestogens (available in pills, gels, patches or vaginal ring);
  • oral contraceptives, to manage irregular periods;
  • antidepressant medications (SSRIs or SNRIs), effective against hot flushes.

However, the need for these therapies should be assessed with a general practitioner and gynaecologist, examining risks and benefits and, above all, monitoring their effects.

One of the most effective non-pharmacological remedies is undoubtedly a change in lifestyle. The adoption of a balanced diet, rich in calcium and vitamin D to prevent osteoporosis, is essential to preserve the general health of the body, as well as regular exercise, which is very useful for combating weight gain and protecting the heart and bones.

For those seeking more specific support, the use of gynaecological supplements may also offer more support during this time, helping to mitigate symptoms. Afragil, developed by Corc.Con. International, is an innovative option in the field of supplements because it supports cell energy metabolism and normal neurological functions thanks to the Calcium it contains. It also protects cells against damage caused by oxidative stress through three unique active ingredients: Vitamin C, Solanum Lycopersicum and Haematococcus pluvialis.


Climacteric is a very special period in a woman’s life. A proper understanding of its symptoms and management strategies can help women navigate this delicate phase with greater peace of mind and well-being.

For this reason, the availability of supplements specifically formulated to alleviate the climacteric symptoms not only satisfies a real need, but also paves the way for a constructive dialogue between companies in the sector and the public, highlighting a commitment to all aspects of women’s well-being.