Afragil is a food supplement for the Gynecological health. Find out details about its clinical studies, pubblications and production.

Afragil is a food supplement based on a specific and harmonized combination of Calcium, Vit. D3, vitamin C, Lycopene from Solanum Lycopersicum, Astaxanthin from Haematococcus pluvialis, Bioflavonoids from Citrus Sinensis.

Afragil is available in chewable tablets; it is recommended to take one tablet per day.

Claims and Safety

It contributes to normal energy-yielding metabolism, to normal neurotransmission (Calcium), to the maintenance of normal muscle function, to the maintenance of normal bones, to normal blood calcium levels and to normal absorption/utilisation of calcium and phosphorus (Vit. D3) and to the protection of the cells from oxidative stress (Vit. C).*

It contributes to the protection of the cells from oxidative stress (Solanum Lycopersicum, Haematococcus pluvialis).**

*EFSA Claim as defined by the EU Regulation 1924/2006
**Botanical Claims as described in the Annex I of the Italian ministerial decree 10 August 2018(BELFRIT)

The product is safe and conforms to Directive 2002/46/EC.

The recommended daily dose should not be exceeded. Food supplements are not a substitute for a balanced and varied diet and a healthy lifestyle. Keep away from children below 3 years old.

Scientific Background

The use of oral contraceptives with high oestrogen concentration or the use of hormones association (oestrogen/progestin) during the central phase of the menstrual cycle showed a significant increase in oxidative stress levels, which can have detrimental effects on blood vessels and microcirculation. Such an effect has to be considered carefully, since the use of oral contraceptives is already associated with an increased risk to develop vein thrombosis, venous thromboembolism and stroke.

A significantly increase in oxidative stress levels is also observed during the perimenopause period (climacteric status), which is a menopausal transition period, when clinical features begin.

During this period of time there are many symptoms which have an impact on the women’s quality of life. There are several natural substances able to counteract OS harmful effects in women, but they have to be specifically and harmonically combined in order to be effective.

Clinical Studies

Thanks to its content in Lycopene from Solanum Lycopersicum and Astaxanthine from Haematococcus pluvialis it has beneficial effects in protecting cells from oxidative stress and relieving symptoms characterized by oxidative stress-related aspects in healthy women.

Panminerva Med. 2010;52(Suppl. 1 to No. 2):1-6

Gynecological supplements