Epilamba Junior
Epilamba Junior is a food supplement for the management of comorbidities in anti-epileptic drug therapy. Effective on brain and gastrointestinal functions.
Epilamba Junior is a patented food supplement based on a specific and harmonized combination of Bacopa monnieri, Eleutherococcus senticosus, Griffonia simplicifolia, Vitamin E, Vitamin C, and Vitamin B6.
Epilamba Junior is the world’s first supplement developed to manage the comorbidities and side effects of antiepileptic therapy in children. It is available in stick form; it is recommended that one stick be taken daily, dissolved in a glass of water. To manage the comorbidities and side effects in adults Epilamba is also available.
Claims and Safety
It contributes to the normal function of the nervous system, to normal psychological functions and to the reduction of tiredness and fatigue (Vit. C and Vit. B6).*
It contributes to preserve memory and cognitive functions (Bacopa monnieri and Eleutherococcus senticosus), to night’s sleep and mental well-being (Bacopa monnieri and Griffonia simplicifolia), it has adaptogenic tonic functions (Eleutherococcus senticosus). It contributes to maintain normal mood (Griffonia simplicifolia).**
* EFSA Claim as defined by the EU Regulation 1924/2006
** Botanical Claims as described in the Annex I of the Italian ministerial decree 10 August 2018(BELFRIT)
The product is safe and conforms to Directive 2002/46/EC.
The recommended daily dose should not be exceeded. Food supplements are not a substitute for a balanced and varied diet and a healthy lifestyle. Keep away from children below 3 years old.
Scientific Background
Epilepsy is a neurological disorder that affects over 70 million people worldwide. Despite the availability of over 20 anti-seizure medications (ASMs) for the symptomatic treatment of seizures, about one-third of patients remain refractory to treatment [1]. Patients with such drug-resistant epilepsy (DRE) have increased risks of premature death, injuries, psychosocial dysfunction and a reduced Quality of Life (QoL), also affecting the caregivers [1]. Equally, these patients facet systemic and neurological adverse events (AEs) associated with polypharmacotherapy. ASMs can cause dose-related AEs, such as drowsiness, fatigue, dizziness, blurry vision, incoordination, and gastrointestinal (GI) symptoms such as constipation or nausea [2;3]. These events are often manageable by lowering the dosage, reducing the number of concomitant drugs, or switching to a better-tolerated ASMs. However, ASMs can also trigger idiosyncratic AEs, including serious cutaneous, hematological, and hepatic reactions, which are more prevalent in children, and typically require the prompt discontinuation of the responsible drug [2]. AEs can affect the physical and mental spheres of patients/caregivers and are not always adequately treated, either because of difficulties in reporting them to the correct specialist or for the fear to incur in polypharmacotherapy; consequently, the management of AEs in DRE represents an unmet medical need. The quest for treatments that contain the incidence of such side effects may result in excessive polypharmacology, which should be avoided especially in children. In this context, the use of food supplements that, without interfering with the pharmacological treatment established by the specialist, could helps the patient to increase compliance with the therapy itself, attenuates comorbidities and in turn improves patients’ QoL.
The intake of natural extract-based compounds has shown promising results in helping to counteract comorbidities (i.e., cognitive deficits or behavioral abnormalities), but they have to be specifically and harmonically combined to exploit synergistic effects.
Cor.Con. International rationally developed Epilamba Junior, a specific and harmonic formula to deal with comorbidities associated to adverse events in antiepileptic drug therapy.
[1]. Rozensztrauch A, Kołtuniuk A. The Quality of Life of Children with Epilepsy and the Impact of the Disease on the Family Functioning. Int J Environ Res Public Health. 2022;19(4):2277.
[2]. Perucca P, Gilliam FG. Adverse effects of antiepileptic drugs. Lancet Neurol. 2012;11(9):792-802.
[3]. Jahromi SR, et al. Gastrointestinal adverse effects of antiepileptic drugs in intractable epileptic patients. Seizure. 2011 May;20(4):343-6.
Clinical Studies
Thanks to its content in specific ingredients (Bacopa monnieri, Eleutherococcus senticosus and Griffonia simplicifolia) it has beneficial effects on cognitive and mood functions, reducing both systemic toxicity and neurotoxicity. It promotes mental well-being (Bacopa monnieri and Griffonia simplicifolia).
Global Pediatrics 15 (2026) 100320
Patents
Epilamba Junior is covered by patents PCT/IB2024/057403
Millions of children around the world face the daily challenges of epilepsy. While existing medications can control seizures, they often come with a heavy burden – comorbidities, related intrinsically to the disease or to the use of drugs – These comorbidities can significantly impact a child’s life, making it difficult to learn, play, and socialise. Imagine a child battling epilepsy, but also facing a different kind of fight – disease’s comorbidities and drugs side effects. The most common ones encountered in the epileptic subjects are: (i) memory deficit; (ii) loss or attenuation of sense of self-worth; (iii) sense of fatigue and exhaustion; (iv) reduced mood; (v) sleep disorders; and (vi) gastrointestinal disorders. The quest for treatments that contain the incidence of such comorbidities may result in excessive polypharmacology, which should be avoided especially in children. In this context, there is a definite need for supplementation that, without interfering with the pharmacological treatment established by the specialist, helps the patient to increase compliance with the therapy itself, attenuates comorbidities and in turn improves patients’ quality of life.
Properties and Indications
Epilamba Junior was rationally formulated and clinically tested with the help of experts to address the medical unmet needs to manage comorbidities in anti-epileptic drug therapy. Epilamba shows promise as a supportive treatment for managing comorbidities and side effects in paediatric patients with epilepsy, potentially improving their quality of life without impacting seizure management. It finds its main application in the patient undergoing specialist treatment for epilepsy and absence and could offer the specialist a useful tool in counteracting some of the most common comorbidities and side effects observed in epileptic subjects. With its well-rounded formulation and promising clinical outcomes, emerges as an innovative approach, offering a complementary, natural adjunct to traditional drug regimens.
Ingredients
- Bacopa Monnieri
- Eleutherococcus senticosus
- Griffonia simplicifolia
- Vitamin E
- Vitamin C
- Vitamin B6
Recommended Use
Epilamba Junior is available in sticks, it is recommended to take one stick per day, dissolved in a glass of water.
Instructions
The recommended daily dose should not be exceeded. Food supplements are not a substitute for a balanced and varied diet and a healthy lifestyle. Keep away from children below 3 years old.
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