Epilamba
Epilamba provide support for the management of comorbidities in anti-epileptic therapy. Promotes Brain & Gastrointestinal Health
Epilamba is a patented food supplement based on a specific and harmonized combination of Bacopa monnieri, Eleutherococcus senticosus, Griffonia simplicifolia, Vitamin E, Vitamin C, and Vitamin B6.
Epilamba is the world’s first supplement developed to manage the comorbidities and side effects of antiepileptic therapy. It is available in stick form; it is recommended that one stick be taken daily, dissolved in a glass of water. To manage the comorbidities and side effects of antiepileptic therapy in children Epilamba Junior is also available.
Claims and Safety
This supplement is designed to support your overall well-being by targeting key areas of health. It helps maintain the normal function of the nervous system, promotes healthy psychological functions, and aids in reducing feelings of tiredness and fatigue, thanks to the combined benefits of Vitamin C and Vitamin B6*.
Additionally, it helps preserve memory and cognitive function, thanks to the power of natural ingredients such as Bacopa monnieri and Eleutherococcus senticosus. For those struggling with sleep or mental balance, it supports restful nights and overall well-being through the synergistic effects of Bacopa monnieri and Griffonia simplicifolia**. The adaptogenic tonic properties of Eleutherococcus senticosus, help the body adapt to stress, while Griffonia simplicifolia contributes to the maintenance of normal mood.
* EFSA Claim as defined by the EU Regulation 1924/2006
** Botanical Claims as described in the Annex I of the Italian ministerial decree 10 August 2018(BELFRIT)
The product is safe and conforms to Directive 2002/46/EC.
The recommended daily dose should not be exceeded. Food supplements are not a substitute for a balanced and varied diet and a healthy lifestyle. Keep away from children below 3 years old.
Scientific Background
Epilepsy is a neurological disorder affecting over 70 million people worldwide. Despite the availability of more than 20 anti-seizure medications (ASMs) for treating seizures, approximately one-third of patients do not respond to treatment, a condition known as drug-resistant epilepsy (DRE) [1]. These patients face higher risks of premature death, injuries, psychosocial challenges, and a significantly reduced quality of life (QoL), which also affects their caregivers[1]. Additionally, they often experience systemic and neurological adverse events (AEs) linked to polypharmacotherapy.
Common dose-related AEs from ASMs, such as drowsiness, fatigue, dizziness, blurry vision, incoordination, and gastrointestinal issues (GI) like constipation and nausea[2;3], can sometimes be managed by adjusting the dosage, reducing the number of medications, or switching to a better-tolerated ASM. However, ASMs can also trigger severe idiosyncratic AEs, including skin, blood, and liver reactions, which are common and may require immediate drug discontinuation[2].
AEs can significantly impact the physical and mental well-being of both patients and caregivers. However, these side effects are not always effectively managed due to underreporting or concerns about increasing the medication burden. Managing AEs in DRE remains an unmet medical need. In this context, food supplements that support therapy adherence, help reduce comorbidities and improve patient QoL without interfering with the prescribed pharmacological treatment could provide valuable support.
The intake of natural extract-based compounds has shown promising results in helping to counteract comorbidities (i.e., cognitive deficits or behavioural abnormalities), but they have to be specifically and harmonically combined to exploit synergistic effects.
Cor.Con. International rationally developed Epilamba, a specific and harmonic formula to deal with comorbidities associated to adverse events in antiepileptic drug therapy.
[1]. Rozensztrauch A, Kołtuniuk A. The Quality of Life of Children with Epilepsy and the Impact of the Disease on the Family Functioning. Int J Environ Res Public Health. 2022;19(4):2277.
[2]. Perucca P, Gilliam FG. Adverse effects of antiepileptic drugs. Lancet Neurol. 2012;11(9):792-802.
[3]. Jahromi SR, et al. Gastrointestinal adverse effects of antiepileptic drugs in intractable epileptic patients. Seizure. 2011 May;20(4):343-6.
Clinical Studies
Thanks to its content in specific ingredients (Bacopa monnieri, Eleutherococcus senticosus and Griffonia simplicifolia) it has beneficial effects on cognitive and mood functions, reducing both systemic toxicity and neurotoxicity. It promotes mental well-being (Bacopa monnieri and Griffonia simplicifolia).
Global Pediatrics 15 (2026) 100320
Patents
Epilamba is covered by patents PCT/IB2024/057403
Millions of adults worldwide face the daily challenges of living with epilepsy. While existing medications can help control seizures, they often come with a significant burden – comorbidities linked to both the disease and the drugs used for treatment. These comorbidities can have a profound impact on an adult’s life, affecting their ability to work, socialize, maintain emotional well-being and enjoy daily activities.
Living with epilepsy often means managing more than just seizures. Adults with epilepsy often face a dual struggle: managing seizures while also dealing with the side effects of treatment and the disease itself. (i) Memory deficits, (ii) reduced sense of self-worth, (iii) fatigue and exhaustion, (iv)low mood, (v)sleep disturbances, and (vi) gastrointestinal issues are among the most common problems encountered. Managing these comorbidities can lead to excessive polypharmacology, which should be avoided, particularly in adults with complex treatment regimens. This underscores the need for supportive solutions that work alongside prescribed treatments without interfering with them.
In this context, targeted supplementation offers a promising approach. When integrated into a specialist’s treatment plan, it can help improve therapy compliance, reduce the impact of comorbidities, and enhance the patient’s overall quality of life.
Properties and Indications
Epilamba was rationally formulated and clinically tested with the help of experts to address the medical unmet needs to manage comorbidities in anti-epileptic drug therapy. Epilamba shows promise as a supportive treatment for managing comorbidities and side effects in patients with epilepsy, potentially improving their quality of life without impacting seizure management. It finds its main application in the patient undergoing specialist treatment for epilepsy and absence and could offer the specialist a useful tool in counteracting some of the most common comorbidities and side effects observed in epileptic subjects. With its well-rounded formulation and promising clinical outcomes, emerges as an innovative approach, offering a complementary, natural adjunct to traditional drug regimens.
Ingredients
- Bacopa Monnieri
- Eleutherococcus senticosus
- Griffonia simplicifolia
- Vitamin E
- Vitamin C
- Vitamin B6
Recommended Use
Epilamba is available in sticks, it is recommended to take one stick per day, dissolved in a glass of water.
Instructions
The recommended daily dose should not be exceeded. Food supplements are not a substitute for a balanced and varied diet and a healthy lifestyle. Keep away from children below 3 years old.
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